Wednesday Matchup: Cubs (Hamels) at Rockies (Senzatela), Coors Field, 1:10 p.m.

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Antonio Senzatela starts for the Rockies in Wednesday's series finale. He is 2-0 with a 2.89 ERA in his last three starts at Coors Field. He is starting against the Cubs for the first time since 2017 when he started at both Coors Field and Wrigley Field. He picked up a win at Coors Field, allowing two runs on five hits and three walks, striking out four, in six innings.

Hamels is 1-1 with a no decision in his last three starts at Coors Field with a 2.66 ERA. He is 1-1 in his last two starts this season, both against the Cardinals. The loss came in St. Louis when he allowed one unearned run in seven innings. He won at Wrigley Field with eight shutout innings.​

Hamels has a long history against Ian Desmond (.197) and Daniel Murphy (.321). Senzatela has limited Javier Baez to one hit in six at-bats, and Kris Bryant to two hits in seven at-bats. The rest of the Cubs, however, are 10-for-27 against him.